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Certain dietary patterns, including prolonged fasting and high-fat low-carbohydrate dieting, can produce ketosis, in which acetone is formed in body tissue.
Certain health conditions, such as alcoholism and diabetes, can produce ketoacidosis, uncontrollable ketosis that leads to a sharp, and potentially fatal, increase in the acidity of the blood.
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It is used as one of the volatile components of some paints and varnishes.
It is a common solvent for rinsing laboratory glassware because of its low cost and volatility.
Despite its common use as a supposed drying agent, it is not effective except by bulk displacement and dilution.
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Acetone was first produced by alchemists during the late Middle Ages via the dry distillation of metal acetates (e.g., lead acetate, which produced "spirit of Saturn" (since the alchemical symbol for lead was also the astrological symbol for the planet Saturn)).